7 research outputs found

    Geometric and photometric affine invariant image registration

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    This thesis aims to present a solution to the correspondence problem for the registration of wide-baseline images taken from uncalibrated cameras. We propose an affine invariant descriptor that combines the geometry and photometry of the scene to find correspondences between both views. The geometric affine invariant component of the descriptor is based on the affine arc-length metric, whereas the photometry is analysed by invariant colour moments. A graph structure represents the spatial distribution of the primitive features; i.e. nodes correspond to detected high-curvature points, whereas arcs represent connectivities by extracted contours. After matching, we refine the search for correspondences by using a maximum likelihood robust algorithm. We have evaluated the system over synthetic and real data. The method is endemic to propagation of errors introduced by approximations in the system.BAE SystemsSelex Sensors and Airborne System

    CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

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    Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

    CIBERER: Spanish national network for research on rare diseases: A highly productive collaborative initiative

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    13 páginas,1 figura, 3 tablas, 1 apéndice. Se extraen los autores pertenecientes a The CIBERER network que trabajan en Centros del CSIC del Appendix ACIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research.This study has been funded by Instituto de Salud Carlos III (ISCIII) and Spanish Ministry of Science and InnovationPeer reviewe

    Geometric and photometric affine invariant image registration

    No full text
    This thesis aims to present a solution to the correspondence problem for the registration of wide-baseline images taken from uncalibrated cameras. We propose an affine invariant descriptor that combines the geometry and photometry of the scene to find correspondences between both views. The geometric affine invariant component of the descriptor is based on the affine arc-length metric, whereas the photometry is analysed by invariant colour moments. A graph structure represents the spatial distribution of the primitive features; i.e. nodes correspond to detected high-curvature points, whereas arcs represent connectivities by extracted contours. After matching, we refine the search for correspondences by using a maximum likelihood robust algorithm. We have evaluated the system over synthetic and real data. The method is endemic to propagation of errors introduced by approximations in the system.EThOS - Electronic Theses Online ServiceBAE Systems : Selex Sensors and Airborne SystemsGBUnited Kingdo

    Geometric and photometric affine invariant image registration

    No full text
    This thesis aims to present a solution to the correspondence problem for the registration of wide-baseline images taken from uncalibrated cameras. We propose an affine invariant descriptor that combines the geometry and photometry of the scene to find correspondences between both views. The geometric affine invariant component of the descriptor is based on the affine arc-length metric, whereas the photometry is analysed by invariant colour moments. A graph structure represents the spatial distribution of the primitive features; i.e. nodes correspond to detected high-curvature points, whereas arcs represent connectivities by extracted contours. After matching, we refine the search for correspondences by using a maximum likelihood robust algorithm. We have evaluated the system over synthetic and real data. The method is endemic to propagation of errors introduced by approximations in the system.EThOS - Electronic Theses Online ServiceBAE Systems : Selex Sensors and Airborne SystemsGBUnited Kingdo

    Perfil dermatoglí­fico y somatotipo en atletas universitarios

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    The present study characterized the dermatoglyphic profile and somatotype of 12 university athletes, belonging to the athletics team of the Santo Tomás University, Bogotá Campus. Dermatoglyphic characteristics were identified, according to the Cummins & Midlo (1942) protocol, to obtain the types of designs of digital impressions (A = 0.3; ± 0.7; L = 6.9 ± 2.6 and W = 2.8 ± 2.9) and in turn the sum of the total number of lines (SCTL = 170.6 ± 95.1) and finally, the delta index (D10 = 12.4 ± 3.3). For the somatotype, the Heath & Carter protocol (1990) was taken into account. Endomorphy in (2.5 ± 0.9); Mesomorphy (5.3 ± 0.9) and Ectomorphy (3.1 ± 1). The dermatoglyphic profile of each of the athletes evidenced the presence of the ectomorphic somatotype over the others. This determined the importance of this technique as a genetic tool in the optimization of sports strategies and orientations. The need to continue with these investigative processes is fundamental for the academy, sports processes, athletes, and Colombian, university, and professional sport.El presente estudio caracterizó el perfil dermatoglí­fico y somatotipo de 12 atletas universitarios, pertenecientes a la selección de atletismo de la universidad Santo Tomás, sede Bogotá. Se identificaron las caracterí­sticas dermatoglí­ficas, acorde al protocolo de Cummins & Midlo (1942) para obtener los tipos de diseños de las impresiones digitales  (A= 0,3; ± 0,7; L= 6,9 ± 2,6  y W= 2,8 ± 2,9) y a su vez la suma de la cantidad total de lí­neas ( SCTL= 170,6 ± 95,1) y por último, el í­ndice delta (D10= 12,4 ± 3,3). Para el  somatotipo, se tuvo en cuenta  el protocolo de Heath & Carter (1990). Endomorfia en (2,5 ± 0,9); Mesomorfia (5,3 ± 0,9) y Ectomorfia (3,1 ± 1). El perfil dermatoglí­fico de cada uno de los deportistas, evidenció la presencia del somatotipo ectomorfo sobre los otros. Esto determinó la importancia de esta técnica como herramienta genética en la optimización de estrategias y orientaciones deportivas. La necesidad de seguir con estos procesos investigativos es fundamental para la academia, los procesos deportivos, los deportistas y al deporte Colombiano, universitario y profesional.O presente estudo caracterizou o perfil dermatoglí­fico e o somatótipo de 12 atletas universitários pertencentes í  equipe de atletismo da Universidade Santo Tomás, sede de Bogotá. As caracterí­sticas dermatoglí­ficas foram identificadas, de acordo com o protocolo Cummins & Midlo (1942), para obter os tipos de projetos de impressões digitais (A = 0,3; ± 0,7; L = 6,9 ± 2,6 e W = 2,8 ± 2,9) e, por sua vez, a soma do número total de linhas (SCTL = 170,6 ± 95,1) e, finalmente, o í­ndice delta (D10 = 12,4 ± 3,3). Para o somatótipo, foi considerado o protocolo de Heath e Carter (1990). Endomorfia em (2,5 ± 0,9); Mesomorfia (5,3 ± 0,9) e Ectomorfia (3,1 ± 1). O perfil dermatoglí­fico de cada atleta evidenciou a presença do somatótipo ectomórfico sobre os demais. Isso determinou a importãncia dessa técnica como ferramenta genética na otimização de estratégias e orientações esportivas. A necessidade de continuar com esses processos investigativos é fundamental para a academia, processos esportivos, atletas e esportes colombianos, universitários e profissionais

    Liraglutide and Renal Outcomes in Type 2 Diabetes.

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    BACKGROUND: In a randomized, controlled trial that compared liraglutide, a glucagon-like peptide 1 analogue, with placebo in patients with type 2 diabetes and high cardiovascular risk who were receiving usual care, we found that liraglutide resulted in lower risks of the primary end point (nonfatal myocardial infarction, nonfatal stroke, or death from cardiovascular causes) and death. However, the long-term effects of liraglutide on renal outcomes in patients with type 2 diabetes are unknown. METHODS: We report the prespecified secondary renal outcomes of that randomized, controlled trial in which patients were assigned to receive liraglutide or placebo. The secondary renal outcome was a composite of new-onset persistent macroalbuminuria, persistent doubling of the serum creatinine level, end-stage renal disease, or death due to renal disease. The risk of renal outcomes was determined with the use of time-to-event analyses with an intention-to-treat approach. Changes in the estimated glomerular filtration rate and albuminuria were also analyzed. RESULTS: A total of 9340 patients underwent randomization, and the median follow-up of the patients was 3.84 years. The renal outcome occurred in fewer participants in the liraglutide group than in the placebo group (268 of 4668 patients vs. 337 of 4672; hazard ratio, 0.78; 95% confidence interval [CI], 0.67 to 0.92; P=0.003). This result was driven primarily by the new onset of persistent macroalbuminuria, which occurred in fewer participants in the liraglutide group than in the placebo group (161 vs. 215 patients; hazard ratio, 0.74; 95% CI, 0.60 to 0.91; P=0.004). The rates of renal adverse events were similar in the liraglutide group and the placebo group (15.1 events and 16.5 events per 1000 patient-years), including the rate of acute kidney injury (7.1 and 6.2 events per 1000 patient-years, respectively). CONCLUSIONS: This prespecified secondary analysis shows that, when added to usual care, liraglutide resulted in lower rates of the development and progression of diabetic kidney disease than placebo. (Funded by Novo Nordisk and the National Institutes of Health; LEADER ClinicalTrials.gov number, NCT01179048 .)
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